Zip Drive Causing Error Message

[Chandler]

Every so often, when I start PowerDVD I get a message saying there is no disk in the drive.  please insert a disk......  This is caused by my internal 250MB Zip drive.

I find that if I change the drive letter through Disk Management, then this error message stops, but every so often it will do it again.  I used to notice this on Windows 2000 too, but it never occurs on Windows 98.